2008 Annual Meeting Abstracts
Racial Differences And Timing Of Anastomotic Strictures Following Radical Retropubic Prostatectomy
albert ndzengue*
Charing Cross Hospital, london, United Kingdom
Introduction:
Anastomotic stricture is a potential complication following radical prostatectomy. The incidence within different ethnic groups has not been studied. Endoscopic bladder neck incision or dilation is commonly used as the initial management of anastomotic strictures.
Methods:
We retrospectively studied case notes of 718 patients who had radical prostatectomy between 1994 and 2007 by one urological surgeon. The incidence of anastomotic strictures and the time to clinical presentation in white, black and asian men were recorded. Odd ratios and linear regression analysis were used to investigate potential differences.
Results:
Anastomotic strictures were observed in 65 patients (9.05%). The incidence of strictures in black patients was significantly higher (p=0.04) than in whites. There was no significant difference in the time to clinical presentation between all three ethnic groups. Whites developed strictures after 6 months, black after 6.83 months and Asians after 5.66 months in the absence of evidence of cancer recurrence (normal PSA). There was no difference in the numbers of endoscopic therapeutic procedures performed in each group (1.70 in whites versus 2 in blacks versus 1.66 in Asians).
Conclusions:
Black patients are relatively prone to anastomotic strictures following radical prostatectomy. The mechanism explaining this tendency could be similar to that of cheloid scars commonly observed in that ethnic group.
