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Periprostatic Nerve Blocks For Prostate Biopsies Are Associated With A Decreased Risk Of Vasovagal Reactions and With Decreased Biopsy Recovery Times
Jeffrey C Lou, Michael McManus, Diane Ibanez, Daniel S McPartlin, Adam P Klausner, Vidal M Despradel, B Mayer Grob
VIRGINIA COMMONWEALTH UNIVERSITY HEALTH SYSTEMS, RICHMOND, VA

Introduction: The use of a periprostatic nerve block (PNB) prior to prostate biopsy has been previously demonstrated to reduce patient discomfort. The goal of this investigation was to determine whether PNB’s affected procedure times, recovery times, or the incidence of vasovagal (VV) events.
Methods: A retrospective review of prostate biopsy logs over a one year period (2004-2005) at our institution was performed. Data was collected regarding age, number of cores, procedure and recovery time, VV events, and the use of PNB’s. Unpaired t tests and Chi square tests were used for statistical analysis.
Results:
GroupAverage
Procedure Time (min)
Average
Recovery Time (min)
Average
Total Time (min)
Average # Biopsy CoresAverage
Age
(years)
# VV events
PNB
(n=150)
1251812.6652
No PNB (n=138)10
p=0.03
7
p=0.006
1710.56613
p=0.01

The average increase in recovery time in patients experiencing a VV event was 16 minutes and one patient with a VV reaction required an emergency room evaluation for a fall with loss of consciousness.
Conclusions: These data demonstrate that while the administration of PNB's for prostate biopsies can result in lengthened procedure times, this is offset by the longer recovery times for patients who receive no nerve block. Moreover, VV events occur more frequently without PNB’s and not only lengthen recovery times significantly, but also expose patients to potentially adverse events. Consideration should be made to include the use of PNB’s with every prostate biopsy.


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